Effect of Aqueous Allium cepa and Ixora brachiata Root Extract on Leishmania major Promastigotes

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Effect of Aqueous Allium cepa and Ixora brachiata Root Extract on Leishmania major Promastigotes

BACKGROUND Leishmaniasis is a major worldwide public health problem with about two to three million humans threatened by this disease annually. Allium cepa (onion) is an important dietary vegetable and was used as a herbal medicine for centuries. The root of Ixora brachiata is medicinally important. OBJECTIVES The aim of this study was to investigate the anti-Leishmania effect of the ethanoli...

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effect of aqueous allium cepa and ixora brachiata root extract on leishmania major promastigotes

conclusions this study showed that aqueous allium cepa and ixora brachiata root extracts as natural products could be used as alternative drugs in treatment of leishmaniasis. results among tested plant extracts, ixora brachiata root extracts revealed the best activity against leishmania major promastigotes with ic100 value of 2.5 mg/ml and ic50 value of 0.078 mg/ml. patients and methods the par...

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effect of caparis spinosa root extract on promastigotes and amastigotes of leishmania major

this study was carried out to identify the efficacy of caparis spinosa root extract on promastigotes and amastigotes of leishmania major . caparis spinosa extracts were prepared. promastogotes of  l.major (1×10 6 parasites/ml)were incubated at 26 ºc for 24,48 and 72hours in fresh medium(nnn), in absence or presence of different concentrations (0.1,0.3,0.5,0.7,0.9 mg/ml) of caparis spinosa metha...

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Effects of the flower extract of Ixora coccinea Linn. On the meristematic cells of Allium Cepa

The aqueous extract of flowers of I. coccinea was evaluated for its cytotoxic and mutagenic effects on the meristematic cells of onion root tip. The percentage of abnormalities was found to increase with the increase in the concentration of the extract from 20 to 60 mg/ml. With 80 mg/ml completed arrest or total inhibition of cell division was observed. The major abnormalities were unprinted ch...

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Effects of Methanolic Extract of Arctium lappa Root on Promastigotes and Amastigotes of Leishmania major (in vitro)

ABSTRACT        Background and Objective: Leishmania major is a flagellate protozoan parasite causing cutaneous leishmaniasis. Although pentavalent antimony compounds are the first-line drugs for leishmaniasis, their application is often accompanied by numerous limitations and side effects. Therefore, it is necessary to seek drugs of herbal origin that have fa...

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ژورنال

عنوان ژورنال: Jundishapur Journal of Natural Pharmaceutical Products

سال: 2014

ISSN: 1735-7780,2228-7876

DOI: 10.17795/jjnpp-15442